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DNA match eludes investigators in Nancy Guthrie case, sheriff confirms
By Belle Carter // Feb 19, 2026

  • The Pima County Sheriff's Department confirmed that DNA from gloves found near Nancy Guthrie's residence did not match any profiles in the Combined DNA Index System (CODIS).
  • Despite the negative DNA match, law enforcement and the Guthrie family remain committed to finding Nancy and continue to appeal to the public for any information.
  • The sheriff's department is analyzing additional DNA evidence found at the residence, which could provide crucial leads in the investigation.
  • Savannah Guthrie and her family have released social media videos pleading for the public's assistance, and the FBI has offered a $100,000 reward for information leading to Nancy's location or the arrest and conviction of a suspect.
  • The community's support is essential in bringing Nancy home safely. The public is encouraged to remain vigilant and report any information that could help in the ongoing investigation.

In the ongoing search for Nancy Guthrie, the 84-year-old woman who went missing from her Arizona home in late January, a critical piece of evidence has yielded no matches in the Federal Bureau of Investigation's (FBI) database.

The Pima County Sheriff's Department, leading the investigation, confirmed on Feb. 17 that DNA from a glove found near the residence did not match any profiles in the Combined DNA Index System (CODIS). CODIS is an FBI-run national DNA database used by law enforcement to store and share genetic profiles of individuals, according to BrightU.AI's Enoch.

This revelation, while disappointing, has not deterred the dedicated efforts of law enforcement and the Guthrie family, who continue to appeal to the public for any information that could lead to Nancy's safe return.

The Pima County Sheriff's Department announced that DNA evidence from gloves found approximately two miles from Nancy Guthrie's residence was submitted to CODIS and produced no matches.

This news, while a setback, does not rule out the possibility that the gloves were part of the crime scene. Sheriff Chris Nanos, in a separate statement to Fox News, expressed hope that the investigation is inching closer to a breakthrough, despite the negative DNA match.

The sheriff's department also confirmed that there is additional DNA evidence found at the residence that is currently being analyzed. This ongoing forensic work is crucial in piecing together the events leading to Nancy's disappearance.

The department has not provided further details on the nature of this additional evidence, but the public can be assured that every lead is being pursued with diligence and thoroughness.

Family and authorities appeal for public help

In the meantime, broadcast journalist and attorney Savannah Guthrie and her family have released multiple social media videos pleading for the public's assistance in locating Nancy. They have also addressed any alleged abductors in response to purported ransom notes that have been sent to media outlets.

The FBI has offered a $100,000 reward for information leading to Nancy's location or the arrest and conviction of a suspect.

President Donald Trump has also weighed in on the case, emphasizing the gravity of the situation and the potential consequences for those involved.

The Pima County Sheriff's Department has assured the public that any new, significant developments will be promptly communicated through scheduled news conferences.

The search for Nancy Guthrie continues, and the community's support is crucial in bringing her home safely. The negative DNA match from the glove is a setback, but it does not diminish the resolve of law enforcement and the Guthrie family. Every piece of evidence, no matter how small, is being meticulously examined to ensure that justice is served.

The public is encouraged to remain vigilant and to report any information that could help in the ongoing investigation.

Watch the video below where Pima County Sheriff Chris Nanos declares that job no. 1 is to find Nancy Guthrie.

This video is from the NewsClips channel on Brighteon.com.

Sources include:

TheEpochTimes.com

X.com

BrightU.ai

Brighteon.com



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